منابع مشابه
Thyroid hormones and thermogenesis.
An extensive review article on thyroid hormone published nearly 40 years ago (Barker, 1951) might have led one to suppose that little could be added to the subject of thyroid hormones and thermogenesis. However, a large number of new ideas have since emerged with respect to the mechanisms of action of thyroid hormones, although there is still considerable uncertainty as to how they function at ...
متن کاملA study of the relationship between thermogenesis and thyroid hormones.
To investigate the relationship between serum T3 levels and thermogenesis in euthyroid subjects, the conversion of T4 to T3 was partially blocked over a period of 3 weeks by weekly ingestion of 2 g iopanoic acid. Serum T3 decreased by 56 +/- 6 ng/100 ml without affecting the metabolic rate or total heat loss. Because an increase in serum T4 levels was observed (3.70 +/- 0.2 microgram/100 ml), t...
متن کاملA-FABP mediates adaptive thermogenesis by promoting intracellular activation of thyroid hormones in brown adipocytes
The adipokine adipocyte fatty acid-binding protein (A-FABP) has been implicated in obesity-related cardio-metabolic complications. Here we show that A-FABP increases thermogenesis by promoting the conversion of T4 to T3 in brown adipocytes. We find that A-FABP levels are increased in both white (WAT) and brown (BAT) adipose tissues and the bloodstream in response to thermogenic stimuli. A-FABP ...
متن کاملThyroid Hormones and Mesotherapy
Thyroid hormones are the master regulator of body metabolism and growth. They act at molecular level to manipulate genes and cellular functions to balance the basic metabolic rate. They bind to superfamily of nuclear receptors that recognize discrete sequences of DNA and act as transcription factors (Renkawitz et al., 1996). At the cellular level, thyroid hormones act directly on the mitochondr...
متن کاملLipids and thyroid hormones.
C O N T E N T S ABBREVIATIONS I. Tin,on3 HORMONE MECHANISMS A. Calorigenic and anabolic effects B. Thyroid hormone entry into cells II. LIPID METAeOLISM A. Cell lipid composition B. Fatty acid synthesis 1. Protein phosphorylation-dephosphorylation 2. Gene expression C. NADPH generation and oxidation 1. Cytoplasm: NADP+--*NADPH 2. Mitochondria: NADP + + NADH,NADPH + NAD + 3. Microsomes: NADPH-*N...
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ژورنال
عنوان ژورنال: Proceedings of the Nutrition Society
سال: 1990
ISSN: 0029-6651,1475-2719
DOI: 10.1079/pns19900024